: the all-trans isomer of retinoic acid that is applied topically for the skin to treat acne vulgaris also to reduce facial wrinkles, roughness, and pigmented spots and that is administered orally to induce remission of acute myelogenous leukemia in which more than 50 percent the cells are malignant promyelocytes http://www.arcadetrainer.com/index.php?params=profile/view/2372863/