Pretreatment with probenecid minimizes both of those the natriuresis and hyperreninemia made by Bumex. This antagonistic outcome of probenecid on Bumex natriuresis will not be resulting from a direct action on sodium excretion but is most likely secondary to its inhibitory effect on renal tubular secretion of bumetanide. As a http://bomex19418.worldblogged.com/1138901/considerations-to-know-about-보맥스