Investigation discovered that conolidine and cannabidiol significantly blocked Cav2.2 channels. In the peripheral and central nervous system, Cav2.2 channels can be found predominantly at presynaptic terminals32 and Enjoy critical roles in soreness perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that have an impact on presynaptic Cav2.2 channel https://anatolec160glp0.muzwiki.com/user