MT dynamics are definitely the target of the Microtubule-Concentrating on Agents (MTAs) which Show a dose-dependent anti-proliferative outcome. At higher concentrations, MTAs are cytotoxic; they inhibit cell proliferation by suppressing dynamicity of spindle MTs, which might be essential for proper chromosome separation throughout mobile division, subsequently inducing a mitotic blockage https://benzamide44321.bloginder.com/27508090/666-15-an-overview