Environmental or self-antigens and homotypic interactions cause BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other indicators in the microenvironment and growing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic reports have determined recurrent mutations in genes regulating tumor mobile-microenvironment interactions, whic... https://silasx975wfn3.blogdosaga.com/profile