Finally, clonidine enhances neuraxial opioids and, together with fentanyl, interacts in an additive manner, which often can lessen the dose of every part by 60% for postoperative analgesia. Clonidine treats significant blood pressure by stimulating α2 receptors in the brainstem, which decreases peripheral vascular resistance, reducing blood pressure. It https://www.proleviate.com/post/the-new-pain-killer-conolidine